MadSci Network: Virology |
Charlie, Good question. It turns out that not only viruses but also bacteria and other organisms which invade your body are often quite picky about which cell they first interact with and enter. The easiest answer to give is that each cell type, whether it is a skin cell or a white blood cell has a set of molecules on its outer surface which are found only on that cell. It is these molecules (called receptors) that are recognized by the invader and allow it to attach to and enter that cell. HIV for example recognizes a protein called "CD4" on T-lymphocytes (part of the white blood cell family) while the Varicella zoster virus (chicken pox virus) appears to recognize a protein/sugar molecule (called a proteoglycan) on skin cells. It's also interesting that some organisms (such as a the parasite Toxoplasma) appear to invade every type of human cell known, so whatever its recognizing must be found on all cell types. Thanks for your question Charlie Michael Crawford Oh yeah, I almost forgot. Here's some information on HIV that talks a little about the virus, CD4 interaction, etc. Bye