Re: DHEA-S
Area: Medicine
Posted By: Scott Dietert, M.D. Pathology/Anatomy, retired
Date: Tue Dec 10 17:04:00 1996
Message:
The acronym DHEA means dehydroepiandrosterone, an adrenal cortical
androgenic (male) steroid hormone with far less effect that testosterone.
The basic hormone is capable of being recovered from male urine.
From the University of Maryland some interesting facts/comments:
- The drug is not approved by the FDA.
- Since it is not regulated by the FDA, little is known about its
saftey or any contraindications to its use.
- Its interaction or impact upon other medications, such as contraceptives, is
thus not known either.
- Although DHEA advocates claim that this supplement
can improve mood, increase energy and libido, counteact stress, preserve
muscle, strengthen the immune system, and prevent heart disease and cancer,
NONE OF THESE CLAIMS ARE SUBSTANTIATED BY ANY CONCRETE SCIENTIFIC EVIDENCE;
- Production of DHEA peaks at about age 25 and delines steadily thereafter;
by 85 years of age its production is down about 95%.
- DHEA is a known
precursor of numerous sex steroids, including estrogen and testosterone, but
the specific biological role of DHEA itself is not well understood, because
of the difficulty of separating the effects of DHEA from those of the
primary sex steroids into which it is metabolized.
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