|MadSci Network: Biochemistry|
I make TPN IV bags for a hospital. IV vitamins come in two vials that must be mixed before use. One contains vitamins, the other a buffer. If I know mg/mcg amounts of each vitamin, how would I calculate the amount of buffer needed to bring pH to about 7.4 (that of blood)? In practice, the total volume of IV solution is 5ml vitamin & 5ml buffering agent injected into no less than 500ml IV bag. My question boils down to (1) how do I calculate "acidity" for each vitamin, then (2) how do I calculate amount of buffer (citric acid, sodium citrate, NaOH, ect) needed to bring pH up to 7.4? Thanks
Re: I.V. vitamins must be reduced to pH close to blood, HOW?
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