|MadSci Network: Biochemistry|
In glycolysis, NAD*H enters the mitochondria to produce ATP in the presence of oxygen. In the absence of Oxygen, NAD*H is shuttled to pyruvate. According to "Metabolism at a Glance," once inside the mitochondrial membrane NAD*H is converted using maltase and other cofactors. Many of these cofactors are oxadized. Is it possible that production of the shuttle responsible for taking NAD*H to the mitochondria is triggered by the presence of oxygen? Perhaps chemosynthesis is the key and NAD*H is attracted by the concentration gradient? How does NAD*H "know" whether to contunue aerobically or anaerobically? All resources have skirted around this question, perhaps you can find out if the answer is known.
Re: Glycolysis: How does NAD*H 'know' oxygen is present in the mitochondria
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