MadSci Network: Immunology |
Both cells are derived from CD4+ helper T cells. T cells that differentiate into TH1 principally secrete interferon gamma, lymphotoxin and IL-2. These will eventually, mainly stimulate the action of macrophage cells. On the other hand, TH2 cells are developed from T cells and mainly secreted IL-4 and IL10. Thier ultimate effect basically are to stimulate production of IG E and eventually stimulate mast cell degranulation. What i am curious about is what is the general major distinction of their effect on infection. Like, is it TH 1 cells more specific for intercellular bacteria infected cells and TH 2 specific for extracellular bacteria infected cells.
Re: What's the difference of TH1 cells and TH2 cells effect?
Try the links in the MadSci Library for more information on Immunology.