MadSci Network: Molecular Biology |
Well, the future of cloning is very hard to forsee. Obviously i'm basically at the same level of understanding in this subject as you are, but i'll throw out some ideas of my own. All cloning that has occurred so far has been via nuclear transplantation followed by in vitro fertilization and implantation into a receptive "mother" animal. Cloning of endangered animals and breeding stock would have it's own genetic pitfalls. First of all, one of the major difficulties of expanding small populations of endangered species is genetic homozygosity. This would only get worse if animals were cloned to create a large, homozygous population. These sorts of populations are very prone to genetic defects, disease, and other problems associated with inbreeding. The same would hold true with cloning breeding stocks. In may be that commercial cloning will never be a cost effective way to create animals with desired traits. Nature has evolved to be very effective at procreation, whereas cloning could have some unforseen disadvantages in the long evolutionary run. In addition, cloning is much more technically challenging and expensive than allowing animals to do what comes naturally in the first place. As for what type of condition the material will need to be in, only time will tell. At this point, though, entire intact nuclei are required to get viable animals. These nuclei are completely "alive", containing everything necessary to transcribe, control, and replicate their genome. It may very well be impossible to clone animals using only DNA as a starting material. So, that's my two cents worth. Hope it's made you two cents richer. :)
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