MadSci Network: Cell Biology
Query:

Re: Why are cells so small?

Date: Tue May 18 09:38:58 1999
Posted By: Yvonne Buckley, Grad student, Biology, Imperial College London
Area of science: Cell Biology
ID: 922158630.Cb
Message:

Dear Katie,

Thanks for your question - you are right, cells come in a wide variety of 
shapes and sizes but most are tiny. The largest single cells are found 
in single-celled organisms called Protozoa and these are just about 
visible with the human eye (approx 2-3 mm), the most familiar of these is 
Amoeba. Why then do cells not get any bigger than this?

A single cell carries out all of the functions necessary for life, it takes in oxygen and gets rid of carbon dioxide and other wastes, it has to regulate its water absorbtion, take in food, move about, be sensitive to its environment and reproduce. The way a cell exchanges gases (oxygen and carbon dioxide) with the outside world is through diffusion. That means that the gases move into the cell if the concentration of the gas is lower in the cell than in the outside world and the opposite for gases moving out of the cell. This is fine for a small cell which has a large surface area to volume ratio so there is plenty of "surface" for the gases to move across. For large cells however this is not an efficient way of respiring as it takes far too long for gases to move across the cell membrane and deep inside the cell where it is needed.

Yvonne Buckley


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