How does MPP+ cause the death of dopamine receptors in the substantia nigra

Subject: How does MPP+ cause the death of dopamine receptors in the substantia nigra

Date: Thu Apr 22 23:54:27 1999
Posted by Anita Kohli
Grade level: undergrad School: Bryn Mawr College
City: Bryn Mawr State/Province: PA Country: USA
Area of science: Neuroscience
ID: 924843267.Ns

Message:


I know that MPTP was studied a while back because, it is 
converted to MPP+ by monoamine oxidase, and that it has ben found 
that MPP+ casues the death of dopamine receptors...is any other 
information known about this... I keep looking and I can't find 
much.. maybe you guys will have an idea. 
Thanks. 
Anita:)

Re: How does MPP+ cause the death of dopamine receptors in the substantia nigra

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