MadSci Network: Medicine |
The answer to your question of "what's the reason behind menstrual blood not clotting" is put very simply. Normal menstrual blood does clot, menstrual blood contains not only blood but also tissue from the lining of the uterus. The hormones estrogen and progesterone make the eggs in the ovaries "mature" and prepares the uterus for pregnancy. Once a month, one egg matures and leaves one of the ovaries, heading down one of the fallopian tubes toward the uterus. During this time, while the egg is traveling, the uterus begins to build up its lining with extra blood and tissue, making the walls of the uterus thick and cushioned. If the egg reaches the uterus and is fertilized by sperm, it attaches to the cushiony wall of the uterus, where it uses the extra blood and tissue to nourish and protect itself as it slowly develops into a baby. In most cases, though, the egg isn't fertilized by sperm, and is just passing through instead. When this happens, the egg dissolves and the uterus, no longer needing the cushioning for the egg, sheds the extra tissue lining. The blood and tissue leave the uterus, going through the vagina on its way out of the body. This is a menstrual period. This cycle (an egg being released once a month and the uterus building itself up and then shedding its lining when it's not needed) will happen almost every month for several more decades - until a woman no longer releases eggs from her ovaries. http://www.gynalternatives.com/causes.htm To answer the second part of your question ,"Are there any blood coltting factors missing in menstrual blood?" There are several conditions where blood clotting factors may be missing but I am only going to refer to one of them which is the most common bleeding disorder in women and girls. It is called von Willebrand disease, an inherited disorder that affects up to 3% of the population, or approximately 2.6 million people. Half of these people are women. Von Willebrand disease is caused by a defect in or a deficiency of a blood clotting protein called von Willebrand factor. von Willebrand disease causes bleeding into the skin and from mucous membranes, which line the nose, gums and the gastrointestinal and genitourinary tracts. Symptoms of von Willebrand disease include frequent or prolonged nosebleeds,easy bruising, bleeding gums, bleeding following dental work, and heavy menstrual periods. There is no cure for von Willebrand disease, but it can be treated. Minor bleeds may not need treatment, but more serious bleeding problems (such as very heavy menstrual periods) can be regulated by taking birth control pills or other hormones. http://womenshealth.miningco.com/msub31.htm?TMog=62829403091525 http://biomed.redcross.org/home/cmponent.htm Check out the internet sites I have included I am sure you will enjoy the references. I want to thank you for taking the time to send in a question to the MadSci Network and I hope I have given you enough information concerning your question. June Wingert RM(NRM) ASM Center of Comparative Medicine Baylor College of Medicine One Baylor Plaza Houston, Texas
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