MadSci Network: Immunology
Query:

Re: How does the shark immune system work?

Date: Fri Jan 7 15:30:47 2000
Posted By: Tinsley Davis, Grad student, Microbiology, University of Wisconsin Madison
Area of science: Immunology
ID: 945283368.Im
Message:

Quentin,
	Browsing the list of unanswered questions, I found one that, as an 
immunologist-in-training,  I just couldn't resist-yours!  I hope the 
following suggestion is not too late to be helpful.

	You can imagine that an effective immune system is needed for survival.  
Sharks are ancient creatures that have been on the earth for 450 million 
years.  They possess a highly effective immune system, and scientists 
studying shark immunity are learning new things about the human immune 
system as a result.  One of my favorite Scientific American articles 
addresses just the topic you're looking for and should be easily found at 
most public libraries.

	In the November 1996 issue, Gary W. Litman describes his group's 
research into the similarities and differences between shark and human 
immunity.  The article is well-written with excellent illustrations and 
sufficient background-I won't spoil the fun or challenge by summarizing it 
here.  Also, the author lists additional resources that should be 
accessible in either your public library or a local university library.

Good luck and don't hesitate to check back with us if you have additional 
questions!
-Tinsley

"Sharks and the Origins of Vertebrate Immunity"  Gary. W. Litman
Scientific American
November 1996
pp.67-71



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