MadSci Network: Biochemistry |
Dear Fred, The basics of the Scatchard plot derive from the fact that the equation for the binding of a ligand to a receptor has the same form as the binding of a substrate to an enzyme, the more familiar Michaelis-Menton equation. I would recommend you read Athel Cornish-Bowden's "Fundementals of Enzyme Kinetics" (Portland Press, London 1995). They have a web page at http://www.portlandpress.com/books/titles.htm. I would thoroughly recommend this book, in my opinion it is the best available on the subject.
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