Subject: What are the pathophysiological responds due to smoking?

I am interested to know about the effect of smoking on the cardio-
respiratory system especially on how smoking might impair normal cardio-
respiratory mechanism in a normal person especially in strenous physical 
exercise.
I am also extremely grateful if someone might be able to explain to me the 
IMMEDIATE effect of smoking e.g. the component effect of NICOTINE on heart 
function espcially in ARRYTHMIA
I am also interested to know about the pathology on CHRONIC AIRFLOW 
OBSTRUCTION and ATHEROSCLEROSIS due to smoking.

Thanks alot

Re: What are the pathophysiological responds due to smoking?