|MadSci Network: Chemistry|
The analysis of caffeine in coffee, soda, etc. is quite complex due to the interference of other alkaloids present, and a variety of degradations products. The latest method is by isocratic high performance liquid chromatography, used with standands, seems to be very good. Reference: Barbas, C., Garcia, A.,Saavedra, L, and Castro, M. J. Chromatography A, 870 (1+2), 2000, pp.97-103.
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