MadSci Network: Biochemistry
Query:

Re: how does glumatine help in promoting muscle building and heal broken limbs?

Date: Tue May 30 15:31:43 2000
Posted By: Lyle Burgoon, Grad student, Pharmacology and Toxicology, College of Human Medicine, Michigan State University
Area of science: Biochemistry
ID: 955421479.Bc
Message:

Sam, thanks for your question.

The simplest answer to your question is that glutamine is an amino acid. Glutamine is essential in the production of proteins. Proteins are basically the workhorses of the cell, and ultimately the human body. If we are missing just one of the amino acids, the body will not function properly.

So how does glutamine help to heal bones? Well, glutamine is essential for the body to create the proteins (or enzymes) responsible for bone remodeling – this includes bone destruction and bone formation.

Glutamine helps the body “build” muscle mass. The mechanism here is rather complex, but in simple terms it’s through formation of proteins. When one builds muscle mass, he/she isn’t increasing the number of muscle cells, but rather just increasing the size of the sarcomeres (this is a very, very, grossly simplified explanation). So, in order to increase the size of the sarcomere the muscle cell needs to build more proteins (the architectural framework for the cell). In order to build more proteins, the cell needs all of the amino acids that that messenger RNA (mRNA) codes for [in translation] – and this includes glutamine.

So there ya go. I hope that answers your question. Thanks again!



Lyle D. Burgoon
Graduate Assistant
Department of Pharmacology and Toxicology
College of Human Medicine
National Food Safety and Toxicology Center
Michigan State University


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