|MadSci Network: Medicine|
The bacteria that causes leprosy in humans (Mycobacterium leprae) can be injected into the footpads of mice, start to grow, and create sores similar to that seen in leprosy, but there is no further spreading of disease as in humans. The best animal model to date, strangely enough, is the armidillo, where a spreading and growth in the peripheral nerves is seen. Animals closely related to humans, such as rhesus monkeys, can also be infected, but are more expensive to house. If you'd like some more techinical primary references on this, check out MEDLINE (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi) and put in 'leprosy AND animal model AND review' Hope this helps Michael Crawford
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