MadSci Network: Anatomy
Query:

Re: What is the process of counting whole cells in adult human body.

Date: Thu Aug 10 15:30:55 2000
Posted By: Pamela Norton, faculty, Dept. of Medicine, Thomas Jefferson Univ.
Area of science: Anatomy
ID: 963069658.An
Message:

Suffice it to say that there is no process for counting all the cells in 
the human body. I cannot verify the source of the number in the original 
posting that is refered to here, 10exp14. However, I am certain that this, 
as well as the estimate of >7.5 trillion cells (7.5 x 10exp12) given at the 
Encylopedia Brittanica site below are just guesses based on some very rough 
extrapolations. Probably the best approach is to take a fragment of known 
weight from a tissue such as liver or brain; you would also need to know 
the weight of the entire tissue. By dissociating the fragment into a cell 
suspension and counting a sample of the cell suspension, one could arrive 
at a reasonable estimate for the total number of cells in that organ. (I'm 
ignoring the difficulty of obtaining human material for such a project.)

My own guess, based on the knowledge that 10exp10 cells can fit comfortably 
in one hand, but that tissues consist of non-cellular material as well as 
cells, is that the correct number is between the two given above.

The following site has many human body factoids, with interesting 
educational links:
 http://www.education-world.com/a_lesson/lesson065.shtml

The treatment at the britannica site is interesting as well: 
 http://www.britannica.com/bcom/eb/article/9/0,5716,42389+2+41468,00.html

Finally, remember that the number of cells in the body is not static; a 
number of cell types (blood, skin and intestinal cells come to mind) are 
constantly cycling, with new cells replacing old. Thus, there may not be a 
single correct number, but rather a normal range.



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