MadSci Network: Microbiology |
Biotechnological production of penicillin Penicillium is harvested in a bioreactor in order to produce penicillin. The media of the culture is enriched with glucose, various salts and soya protein as a nitrogen source. A small quantity of the mucus is then added in the media and is left to grow for a few days (nutrituous media is continuously added culture). When the biomass of the culture is sufficient (depends on the scale of th production) the glucose levels of the media are reduced. The reduction of the glucose levels promote the production of penicillin. The whole process can last up to 20 days or more and provide large amounts of penicillin.
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