MadSci Network: Anatomy
Query:

Re: What parts of the human body are not replaced in the course a lifetime?

Date: Wed Oct 25 18:55:07 2000
Posted By: Brian Edelson, MD/PhD Student
Area of science: Anatomy
ID: 971581578.An
Message:

Your question is a very good one, but unfortunately I don't really know 
the answer.  Every organ in the human body is made up of cells, and in 
general most cells have the capacity to divide if stimulated to do so by 
certain chemical factors.  Some organs are made up of cells which divide 
very frequently, for example the intestines, where the epithelial cells 
along the insides of these organs are basically constantly being replaced 
by fresh cells.  This sort of rapid cell division is also always going on 
the bone marrow, the site where cells divide and give rise to all of the 
different types of cells circulating in the blood.  Another site of rapid 
cell division is the deep layers of the skin, to supply fresh cells to 
replace the outer layers of dead skin which are constantly being sloughed 
off.

Some organs are likely made up of cells which divide only very slowly to 
replace old, dying cells.  Some cells in some organs are most likely very 
long lived (as are neurons within the brain), although the exact rate of 
turnover and replacement is likely not known for certain.

If you'd like to know more about the process of cell division in general, 
a good link that I found is:
 http://mindquest.net/biology/cell-biology/monographs/cell-replication.html

I hope this helps.


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