MadSci Network: Biochemistry
Query:

Subject: Determining the pH level at which buffered and nonbuffered aspirin dissolve

Date: Tue Oct 24 21:06:58 2000
Posted by Jennifer
Grade level: 10-12 School: Kingston Collgiete and Vocational Institude
City: Kingston State/Province: Ontario Country: Canada
Area of science: Biochemistry
ID: 972436018.Bc
Message:

Buffered ASA painkillers do not dissolve in the stomach, but rather, the 
small instestine.(what is the average pH level of the small intestine?) 
Non-buffered ASA painkillers dissolve in the stomach. This is due to the 
inert stuff that the manufacturers put in the tablets, that will make the 
buffered ASA painkiller release its ASA, and dissolve in a more basic 
enviroment (such as the small intestine). Is there a way (or ways) in which 
I can determine the pH level at which buffered ASA painkillers dissolve in 
(and get into the body)? Would the procedures also apply in determining the 
pH level at which a regular ASa painkiller would dissolve in? 


Re: Determining the pH level at which buffered and nonbuffered aspirin dissolve

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