|MadSci Network: Science History|
Hi Jen, This is a great question! I think what your dad meant when he said you have royal blood (other than being his little princess), is that if you have AB+ blood, you can receive a blood transfusion from ANY other type of blood-- A, B, AB or O, either positive or negative, and you can only give blood to people with AB+ blood. Therefore, people are always giving to you, and you don't have to give to many other people--kinda like royalty. Let me explain why. If you have type A- blood, it means your red blood cells have the A marker on the surface, and no Rh factor. If you were to receive blood with the B surface marker (B-, B+, AB+ or AB-), your immune system would recognize the blood as foreign, and make it clump up! If you were to receive type A+ blood, the same thing would happen, due to the presence of the Rh marker. If you have type B+ blood, you could receive blood which was B+, B- (the - means that the Rh factor isn't there, so there's nothing to react with), O+ or O-. The O blood type doesn't have any surface marker, so like before, there's nothing to react with. OK--so if you have AB+ blood, you have all of the different kinds of markers on the surface of your blood cells-- A, B and the Rh factor. This means you could get blood from anyone, but you could donate only to people who also have AB+ blood. I'm also including another response to a similar question I found in the MadSci archives. Please let me know (email@example.com) if you have any other questions, or if my answer doesn't make sense. Happy Friday! -Sarah Date: Tue May 4 11:47:15 1999 Posted By: David Beck, MadSci Admin Area of science: Genetics ID: 925753350.Ge Message: Blood type indicates what antigens are on the surface of the blood cell. There are three different factors, A, B, and Rh that can be on the surface of the blood cell. If a person has all three factors A, B, and Rh they will not generate an antibody response to any of these factors. This is called the universal acceptor. The can receive blood from anyone. As far as blood type is concerned a person is either Rh- or Rh+ meaning, they either have the Rh factor or they don't. If they have the Rh factor they will not generate antibodies against Rh so the can receive blood from someone who is Rh+ or Rh-. Then when we consider the A and B factors. A person can have either A factor, B factor, A and B factors, or neither. If a person has A and B factors they won't generate antibodies against A or B. If they have A, then they make no A antibodies, and if tehy have B then the make no B antibodies. So an AB person can receive blood with no AB, with A, with B, or with A and B. But an A person can only receive blood from a person with A or no factor. Now if a person doesnt have A or B or Rh, then they can give blood to anyone, but can only receive blood from someone who doesn't have A or B or Rh. Someone without A or B is called O So the bloodtypes are O+, O-, A+, A-, B+, B-, AB+, AB- TYPE Can give to Can receive from O+ O+,A+,B+,AB+ O-,O+ O- all O- A+ A+,AB+ O+,O-,A+,A- A- A+,A-,AB+,AB- A-,O- B+ B+,AB+ O+,O-,B+,B- B- B+,B-,AB+,AB- B-,O- AB+ AB+ all AB- AB+,AB- O-,A-,B-
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