MadSci Network: Neuroscience
Query:

Re: what happenes to the brain and body during and after the use of MDMA {XTC]?

Date: Tue Feb 6 10:51:08 2001
Posted By: Dave Marsen , Grad student, Neurobiology, electrophysiology , University of Amsterdam
Area of science: Neuroscience
ID: 979241043.Ns
Message:

Hi Melissa 

The Designer drugs  MDMA & MDEA (also called "ecstasy" XTC) are both 
powerful SRI's (serotonin re-uptake inhibitor's) (some thing like Prozac but 
much more powerful).
Normally your brain cells communicate with each other through chemical 
substances, one of which is Serotonin. These substances evoke, upon contact 
with the other cell, an electrical signal, which tells the cell what to do. 
The substance Serotonin is involved with a lot of different processes in 
your brain, for example: sleep, eating, emotions (happy feelings, sad 
feelings, angry feelings etc.), your dreams & a lot more.
Normally (in normal brain) your serotonin is secreted by one cell onto the 
other cell, and the excess serotonin is directly taken back into the cell which 
gave the signal (a sort of recycling)… But if you take Drugs like XTC the 
signal (serotonin) stays at the receiver cell for a long time (because it can't 
get back in to the cell who released it)  ….. and the end result will be a 
constant very happy feeling …. (you can compare it a little bit with a 
doorbell, which keeps on ringing)…. So if all your serotonin is released …all 
over ….there is a lot of ringing in your head …this can cause the tactile 
hallucinations ….(e.g. very intense feelings like love, happiness, a 
feeling of inner bliss ) For as long the drug is working.  
Afterwards, when the drug has worn out …("the battery of the bell is 
empty") the Serotonin levels are very low in the brain … and this can also 
cause these tactile hallucinations …(things feel unreal) most people feel 
very "low" very emotional and confused. 
In conclusion: Serotonin is a normal messenger in the brain, but if it is 
massively released, it will cause the tactile hallucinations. 
Some people say that this drug is very harmful, and others will say it is 
an innocent drug. The truth will probably be in the middle … Research has 
shown so far that large doses of XTC, as well as prolonged (mis-) use will 
cause cell death in the brain … and the cells that are lost will never come 
back. So be careful.

Hope to have informed you enough 

Greetings 
Dave 




Current Queue | Current Queue for Neuroscience | Neuroscience archives

Try the links in the MadSci Library for more information on Neuroscience.



MadSci Home | Information | Search | Random Knowledge Generator | MadSci Archives | Mad Library | MAD Labs | MAD FAQs | Ask a ? | Join Us! | Help Support MadSci


MadSci Network, webadmin@www.madsci.org
© 1995-2001. All rights reserved.