Re: How many species of animals have been cloned.

The organisms that have been cloned so far include sheep mice, and cattle.

Sheep:

1. Wilmut I, Schnieke AE, McWhir J, Kind AJ, Campbell KH Viable offspring derived from fetal and adult mammalian cells. Nature 1997 385:810-813 Erratum in: Nature 1997 386:200

Mouse:

1. Wakayama T, Perry AC, Zuccotti M, Johnson KR, Yanagimachi R Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei. Nature 1998 394:369-74

2. Rideout W M, Wakayama T, Wutz A, Eggan K, Jackson-Grusby L, Dausm J Generation of mice from wild-type and targeted ES cells by nuclear cloning. Nature Genetics 2000 24:109-110

Cattle:

1. Kato Y, Tani T, Sotomaru Y, Kurokawa K, Kato J, Doguchi H, Yasue H, Tsunoda Y Eight Calves Cloned from Somatic Cells of a Single Adult. Science 1998 282:2095-2098

2. Renard JP, Chastant S, Chesne P, Richard C, Marchal J, Cordonnier N, Chavatte P, Vignon X Lymphoid hypoplasia and somatic cloning. Lancet 1999 353:1489-91

3. Wells D, Misica PM, Tervit HR Production of Cloned Calves Following Nuclear Transfer with Cultured Adult Mural Granulosa Cells. Biology of Reproduction 1999 60:996-1005

4. Kubota C, Yamakuchi H, Todoroki J, Mizoshita K, Tabara N, Barber M, Yang X Six cloned calves produced from adult fibroblast cells after long-term culture. Proc. Natl. Acad. Sci. USA 97:990-995

Pigs:

1. Polejaeva IA, Chen SH, Vaught TD, Page RL, Mullins J, Ball S, Dai Y, Boone J, Walker S, Ayares DL, Colman A, Campbell KH. Cloned pigs produced by nuclear transfer from adult somatic cells. Nature. 2000 407:86-90.

2. Betthauser J, Forsberg E, Augenstein M, Childs L, Eilertsen K, Enos J, Forsythe T, Golueke P, Jurgella G, Koppang R, Lesmeister T, Mallon K, Mell G, Misica P, Pace M, Pfister-Genskow M, Strelchenko N, Voelker G, Watt S, Thompson S, Bishop M. Production of cloned pigs from in vitro systems. Nature Biotechnology 2000 18:1055-9.

3. Onishi A, Iwamoto M, Akita T, Mikawa S, Takeda K, Awata T, Hanada H, Perry AC. Pig cloning by microinjection of fetal fibroblast nuclei. Science. 2000 Aug 18;289(5482):1188-90.

Goats:

1. Baguisi A, Behboodi E, Melican DT, Pollock JS, Destrempes MM Production of goats by somatic cell nuclear transfer. Nature Biotechnology 1999 17: 456 - 461

Yours,

Paul Szauter
Mouse Genome Informatics