MadSci Network: Genetics

Subject: Is it likely my expected grandchild will inherit CMT Disease?

Date: Thu Apr 12 21:16:32 2001
Posted by Cindy
Grade level: nonaligned School: No school entered.
City: Windsor State/Province: Nova Scotia Country: Canada
Area of science: Genetics
ID: 987124592.Ge

My son and his wife are expecting their first child.  She is 21 years old, and 
she has Charcot-Marie-Tooth Disease.  Her father also has CMTD--his onset was at 
approximately 40--45 years of age.  My son's wife, at 21, already has 
significant symptoms--drop foot, affected wrists, ankles, 'hunched back', etc.  
I realize (or I believe) there is a 50/50 chance of the baby inheriting CMT, 
however, I am wondering if the chances are greater or lesser with her being a 
daughter inheriting from her father, as opposed to if it were our son being the 
carrier?  Any information you can provide would be greatly appreciated.  I could 
not find the answer to this specifically by searching your site.  Thank you.

Re: Is it likely my expected grandchild will inherit CMT Disease?

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