MadSci Network: Immunology |
I have done a bit of research on the chickenpox (also called varicella) vaccine in current pediatric textbooks. The vaccine was developed in Japan in the 1970s, and is a live attenuated strain of the virus. This means that the injection contains a live virus which is unable to cause disease, but causes your immune system to mount a response which could later defend against infection with the real, infectious chickenpox virus. According to my reference (listed below), there is no evidence that immunity wanes even as far out as 20 years (that is all of the data available at this time, because the vaccine hasn't been in use longer than this). The current recommendations as far as I can tell do not call for repeated immunizations after 10 years, although as more data becomes available this could be recommended. The vaccine is quite effective at preventing infection (100% effective in blocking serious disease, 86% effective in blocking any disease). In my opinion (and the opinion of the American governing board of Pediatrics), you definitely did the right thing by immunizing your children against chickenpox. It is believed that if 97% of all children are immunized, we could basically wipe out all cases of chickenpox within 30 years. Hope this helps. Reference: Hay, Jr., William W. et al. (eds). Current Pediatric Diagnosis and Treatment, 15th edition. New York: Lange Medical Books/Mcgraw-Hill, 2001.
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