MadSci Network: Medicine

Re: What percentage of people with ulcerative colitis have high cholesterol?

Date: Fri Sep 28 12:40:47 2001
Posted By: Richard Deem, Staff, Inflammatory Bowel Disease, Cedars-Sinai Medical Center
Area of science: Medicine
ID: 1001372270.Me

I could find only one study that addressed the issue of cholesterol levels in Ulcerative Colitis patients. It appears that cholesterol levels are the same as those found in the normal population. Lipids would not be expected to protect against the kind of inflammation seen in the Inflammatory Bowel Diseases, since this inflammation is the result of cellular immunocyte infiltration and response. In fact, the triglyceride levels were higher in the sickest patients. Below is the study citation and abstract:

Unique Identifier


PubMed Identifier



Regoly-Merei A. Ferencz A. Frenkl R. Gergely A. Zajkas G. Antal M.


National Institute of Food Hygiene and Nutrition, Budapest, Hungary.


Effect of fat and retinol loading on serum triglyceride and retinol levels in patients with ulcerative colitis.


Nahrung. 35(1):21-6, 1991.


Serum copper, zinc, selenium, magnesium, calcium, cholesterol, triglyceride and retinol contents were determined in 11 patients with ulcerative colitis and in 20 healthy volunteers. Lipid and retinol loadings were performed as well. No differences were found in serum copper, zinc, calcium and selenium levels between the groups. Serum magnesium levels were somewhat lower in the patients than in the volunteers. During the period of loading, cholesterol levels did not differ between the two groups at any time. Triglyceride levels except for two persons, were higher in patients. Triglyceride curves showed pathological courses in each case. Retinol concentrations in patients remained below the values observed in volunteers. Data suggest a disturbed utilization of fat and retinol in patients with ulcerative colitis.

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