MadSci Network: Genetics
Query:

Re: does gender effect eye color?

Date: Wed Dec 19 09:57:04 2001
Posted By: James Goss, Post-doc/Fellow, Neurology, University of Pittsburgh
Area of science: Genetics
ID: 1007483153.Ge
Message:

As far as I know, gender does not affect eye color.  Eye color, like all 
other physical traits, is determined by your genes.  There are at least 
three different genes that are involved in eye color, though additional 
genes have been suggested to exist based on the wide variety of eye color 
seen in humans.  Gender affects on some trait like eye color would occur 
if one of the genes that controls eye color is on either the X or Y 
chromosomes (these are the sex chromosomes; males have an X and a Y 
chromosome, females have two X chromosomes, males always inherit their X 
chromosome from their mothers and their Y chromosome from their fathers, 
females inherit one X chromosome from each parent).  As far as we know, 
none of the known eye color genes are on the X or Y chromosome.
   While eye color does not appear to have a gender basis, the ability to 
see color does.  The gene that allows us to discriminate between the 
colors red and green is on the X chromosome; if this gene is damaged then 
an individual might be red-green colorblind.  Males are much more likely 
to be colorblind because they only have on X chromosome.  It works like 
this:  you only need one good copy of this gene to see colors properly.  
Therefore if a female has one good copy and one bad copy (because she has 
two X chromosomes) then she can see colors just fine.  Lets say she has 
two sons.  The chance that either son will inherit the X chromosome with 
the bad gene is 50%, therefore one son will probably be colorblind will 
the other son will not (this is the case for myself and my brother who is 
colorblind).  For a daughter to be colorblind, the father must be 
colorblind and the mother must have at least one bad copy of the gene on 
one of her X chromosomes.  This particular combination is much rarer, 
therefore the males are much more likely to be colorblind than females.



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