MadSci Network: Genetics
Query:

Re: I need expert advice on DNA, for a science fair project please.

Date: Wed Jan 2 18:15:59 2002
Posted By: Sabine Heinhorst, Faculty, Chemistry and Biochemistry, The University of Southern Mississippi
Area of science: Genetics
ID: 1006916115.Ge
Message:

Dear LaShawna,

	I can understand your fascination with DNA, since I felt the same 
thrill when I first heard about this molecule in high school a long time 
ago. However, I must also tell you that you have chosen a rather 
complicated subject for a middle school science fair project. Examining 
the effects an organism has on the structure of DNA requires elaborate 
equipment that is available only in university, industrial and government 
research laboratories. Besides, regardless of the type or organism from 
which a DNA sample was obtained, the basic structure of DNA is the same. 
The proteins that bind to DNA, fold, and compact this long molecule vary 
between organisms and between different cell types of the same organism.

	My suggestion to you is to consider, instead, a project such as: 
Can one isolate DNA from plant material using common household items?

The following sites will be helpful in planning your science fair project: 
http://school.discove
ry.com/sciencefaircentral This site gives general 
information about how to design science fair projects, formulate and test 
a hypothesis etc. http://biology.abou
t.com/gi/dynamic/offsite.htm?
site=http://gslc.genetics.utah.edu/students.html%23lab   http://biology.abou
t.com/gi/dynamic/offsite.htm?
site=http://gslc.genetics.utah.edu/students.html%23lab
These are links to the experiment I suggested using dried peas and wheat 
germ, respectively, as starting material for the isolation of DNA. http://biology
.about.com/library/weekly/aa032201b.htm contains several 
other fascinating biology science experiments and general help with 
science fair projects.

Good Luck with your project!

Sabine Heinhorst



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