MadSci Network: Immunology
Query:

Re: Aids and blood Drainage

Date: Sat Jan 12 11:41:45 2002
Posted By: Brian Edelson, MD/PhD Student, WUMS
Area of science: Immunology
ID: 1009989158.Im
Message:

You have a pretty good idea, but here is why it unfortunately wouldn't 
work.

The virus that causes AIDS, the human immunodeficiency virus (HIV), 
infects many cells all throughout the body, not just cells in the blood.  
Examples of some organs where lots of virus-infected cells are present 
include the spleen and lymph nodes.  Draining the blood wouldn't remove 
the infected cells from these organs, and so virus would just return to 
the blood quickly after replacement.

As far as treatment for HIV right now, the best available medicines block 
the replication and infection-process of the virus.  This way, any cells 
which are not yet infected won't become infected by virus spreading from 
already infected cells.  These drugs have proven to be very effective at 
letting people with AIDS live longer and healthier lives.  Unfortunately, 
eventually the virus changes in a way to make the drugs less and less 
effective, and eventually the person will become very sick with AIDS.  
Right now there is no cure, although a great deal of research is going on, 
searching for both a cure and a vaccine, to prevent the spread of the 
virus from person to person.

Hope this helps.


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