| MadSci Network: Biochemistry |
A search of the medical literature revealed 2 articles on caffeine and
calculating "water balance." In one of those, subjects did not consume any
caffeine or related substances for 5 days and then were given 6 cups of
coffee containing 642 mg of caffeine. They had an average negative water
balance of 753 +/- 532 ml over the next 24 hours. (Neuhauser-Berthold,
Beine S, Verwied SC, Luhrmann PM. Coffee consumption and total body water
homeostasis as measured by fluid balance and bioelectrical impedance
analysis. Ann Nutr Metab 1997;41(1):29-36). In the other article, the
authors used figures of 1.17 ml water lost/mg caffeine consumed and
10 ml water lost/ g alcohol in calculating water balance (Stookey JD. The
diuretic effects of alcohol and caffeine and total water intake
misclassification. Eur J Epidemiol 1999 Feb;15(2):181-8). I am not sure of
the derivation of these numbers, although the number for caffeine is the
same as that of the Neuhauser-Berthold et al. article. I could not find
any reference to the caffeine content of different beverages having
different effects; it appears to be a function of the amount of caffeine
present and not the source of the caffeine. Similarly, with alcohol, the
effect seems to be a function of the amount of alcohol consumed and not the
source of the alcohol.
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