MadSci Network: Neuroscience
Query:

Re: What are the characteristics and treatment for Agraphia in children

Date: Mon May 5 16:33:38 2003
Posted By: Doctor X, M.D., Division of Neurosurgery, Division of Neurosurgery-University of Missouri-Columbia
Area of science: Neuroscience
ID: 1050443303.Ns
Message:

Apologies for the delay, but your question involves a bit of semantics.


Alexia: "a" = "without" "lexia" = "reading" in the sense of failure to recognize words. The "proper" term is visual verbal agnosia where "gnosia" comes from "knowledge." Basically, the person can see the letters and words and cannot understand the meaning.
Based on your question, this usually does not affect children. Nevertheless, I will discuss it first. For true alexia to occur, the person must suffer from lesions of the brain--usually strokes. The "basic organization" of the brain involves what are known as "primary" cortices or areas the handle the stimulus. Thus, we have a primary visual cortices at the back of the occipital lobes [Back of head.--Ed.] known as "Brodman's Area 17." These communicate with "secondary" regions which also communicate with further regions. Basically, you have to see the letters, you have to recognize the letters as a coherent thing, you then have to attach a meaning to this coherence. People with alexia lack this ability to process at this level.
An interesting syndrome that demonstrates the processing of vision and language is alexia without agraphia. "Agraphia" means "without writing." A person with this syndrome can write--he can even take dictation--but he cannot read. He cannot read as he writes.
This results from damage that effectively isolates the secondary visual cortices from the areas that interpret language. The areas that interpret language remain connected to the areas that produce language. Thus, the person can still produce language. If you tell him what to write, he can understand it and send it to the area to produce writing. He simply cannot send what he sees to the areas that interpret it.
Dyslexia: Right, since your question refers to children, I suspect you refer to those who suffer from Developmental Dyslexia or Congenital Word Blindness. Back to semantics, the "dys" means a "disfunction of" which more properly describes the problem.
First described in 1896 by Hinshelwood, the problem becomes known in an older child who lackes the ability to understand the meaning of printed words. My primary reference lists a number of papers--which I list after it--that discuss the finer detail of the syndrome.
"The main problem is an inability to read words and also to spell and to write them, despite the ability to see and recognize letters. There is no loss of the ability to recognize the meanings of objects, pictures, and diagrams." (Adams & Victor).
Children appear to lack the awareness that words may be broken down into individual units of sound, or "phonemic unawareness." (Shaywitz, Adams & Victor). Some also have a failure in sequencing, cognitive processing, and breaking words into individual phonemes. A "phoneme" is the smallest part of a word that can convey meaning.
The primary reference notes:
"Often, before the child enters school, reading failure can be anticipated by a delay in attending to spoken words, difficulty with rhyming games, and speech that is characterized by frequent mispronounciations and pucntuated by hesitations and dysfluency, or there may be a delay in learning to speak or in attaining clear articulation." (Adams & Victor).
While I find the discussion of the mechanisms fascinating, it does not address your primary question with regards to treatments. I refer readers to the Adams and Victor reference which is a great source for neurologic problems. With reference to therapy, they do note:
"Lesser degrees of dyslexia are more common than the servere ones and are found in a large segment of the school population. Some 10 percent of schoolchildren have some degree of this disability, but the problem is complex because the condition is unquestionably influenced by the way reading is taught. This disorder is stable and persistent; however, as a result of effective methods of training, only a few children are unable to read at all after many years in school."
They continue that with steady drilling of many hours per week, a cooperative and motivated child can slowly overcome the handicap and read at grade level. They recommend the "Orton phonologic method" as one of the most successful--described in the Rosenberger reference.
I, myself, do not treat this condition in children. If you have difficulty obtaining the reference for therapy, please do not hesitate to contact me through the Mad Scientists and I will see if I can find some specialists who can help you.
--Doctor X
References: Victor M, Ropper AH. Adams and Victor's Principles of Neurology, 7th Ed. New York. McGraw-Hill, 2001 ISBN:0-07-067497-3 (US) 0-07-116333-6
Orton ST. Reading, Writing and Speech Problems in Children. New York. Norton, 1937
Critchley M, Critchley EA. Dyslexia Defined. Springfield, Il. Charles C. Thomas, 1978.
Kinsbourne M. "Disorders of Mental Development," in Menkes JH ed. Textbook of Child Neurology, 5th. Ed. Baltimore, Williams & Wilkins, 1995.
Rutter M, Martin JAM. Clinics in Developmental Medicine. No. 43. The Child with Delayed Speech. London. Heineman, 1972.
Shaywitz SE. "Dyslexia," N Engl J Med 338:307, 1998.
Rosenberger PB. "Learning Disorders," in Berg B, Ed. Principles of Child Neurology. New York, McGraw-Hill, 1996.


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