MadSci Network: Medicine |
Hi, Tracey, This is quite a complicated question to answer. Although I am a Ph.D.-level nutrition person, I decided to talk to one of my colleagues on the faculty here at the University of Hawaii at Manoa. Dr. Sahar Zaghloul is also a nutritionist, but she is, in addition, certified to be a medical doctor (pediatrician) in her home country of Egypt. I was able to talk with her this afternoon, and now I feel more comfortable in answering your question. My problem with answering is that it depends on how the gastric bypass operation is done. The problems with digestion depend on which part of the stomach is left to be functional. The amount of stomach that can be left varies from about 1/2 a stomach to a small pouch about the size of 1-2 fingers. However, if the part that is left comes from the upper stomach (as was the 'fashion' when I was studying nutrition in the mid-late 1980s), then one of the major problems would be 'dumping'of the food into the small intestine, simply because of stomach overload and the inability of the stomach to completely digest (break apart) the food as a larger, whole stomach would. With some of the more severe types of gastrectomy (cutting out of stomach), there can be only a small pouch (the 1-2 fingers-worth). The patient may lose the parts of the stomach lining that produce the enzyme pepsin (a protease...helps digest protein) and the secretion hydrochloric acid (also helps with protein digestion). Thus, when the partially digested food reaches the small intestine, the protein in the food may not be completely ready for further digestion...and may cause too much water to be drawn into the small intestine...and diarrhea can result. Also, there is the risk of the 'dumping' that I mentioned before, because of the smallness of the stomach and the insufficient opportunity for the food to be mechanically broken apart. There can also be a problem with vitamin B- 12 absorption later on in the small intestine, because the intrinsic factor produced by the lining of the stomach may not be made...and this protein compound is necessary for transport of B-12 through the digestive tract to the right place to be absorbed, in the small intestine. Regardless of the type of this operation, it should NEVER to be undertaken lightly...it is dangerous surgery, and can be life- threatening. However, if a person is morbidly obese (where the degree of overweight, itself, is a threat to the person's survival), then sometimes it is the only solution left...all other attempts at losing weight have failed. Whenever there is a problem with digestion (mechanically and chemically breaking apart food in the gastrointestinal tract), there usually is a following set of problems with absorbing nutrients from the food-stuff into the body. For example, if the fat in the food eaten hasn't been broken apart (mechanically) well enough in the stomach into very small lipid/fat droplets, then the enzymes that come from the pancreas and from the small intestine can't complete the digestion of the fat. That means that too much fat-like substances get down further into the large intestine...this creates greasy stools, which can be a nuisance...but, also, there can be substantial kilocalories lost in the fecal matter, but more importantly loss of some components of fat that are essential to the functioning of the body (essential fatty acids). To counteract some of the food-related problems that will happen after a gastrectomy or stomach by-pass, recommendations include avoiding large meals (because of the small stomach capacity), drinking liquids in small amounts and not with meals, and being aware of the possible problem of lactose intolerance (from the sugar in milk...lactose...not being completely digested in the small intestine. Also, the patient must be aware of the possiblity of long-term deficiencies of several B vitamins and may need supplements of several vitamins. I guess, if there is any good news to such a dismal set of circumstances, it is that people really do lose a substantial amount of weight after the by-pass, usually by about 2 years...but, some regain some of the weight lost. Undoubtedly, the operation has saved some people's lives or has vastly improved the quality of the formerly-obese person's life.
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