| MadSci Network: Medicine |
Hi, Tracey,
This is quite a complicated question to answer. Although I am a
Ph.D.-level nutrition person, I decided to talk to one of my colleagues on
the faculty here at the University of Hawaii at Manoa. Dr. Sahar Zaghloul
is also a nutritionist, but she is, in addition, certified to be a medical
doctor (pediatrician) in her home country of Egypt. I was able to talk
with her this afternoon, and now I feel more comfortable in answering your
question.
My problem with answering is that it depends on how the gastric
bypass operation is done. The problems with digestion depend on which
part of the stomach is left to be functional. The amount of stomach that
can be left varies from about 1/2 a stomach to a small pouch about the
size of 1-2 fingers. However, if the part that is left comes from the
upper stomach (as was the 'fashion' when I was studying nutrition in the
mid-late 1980s), then one of the major problems would be 'dumping'of the
food into the small intestine, simply because of stomach overload and the
inability of the stomach to completely digest (break apart) the food as a
larger, whole stomach would.
With some of the more severe types of gastrectomy (cutting out of
stomach), there can be only a small pouch (the 1-2 fingers-worth). The
patient may lose the parts of the stomach lining that produce the enzyme
pepsin (a protease...helps digest protein) and the secretion hydrochloric
acid (also helps with protein digestion). Thus, when the partially
digested food reaches the small intestine, the protein in the food may not
be completely ready for further digestion...and may cause too much water
to be drawn into the small intestine...and diarrhea can result. Also,
there is the risk of the 'dumping' that I mentioned before, because of the
smallness of the stomach and the insufficient opportunity for the food to
be mechanically broken apart. There can also be a problem with vitamin B-
12 absorption later on in the small intestine, because the intrinsic
factor produced by the lining of the stomach may not be made...and this
protein compound is necessary for transport of B-12 through the digestive
tract to the right place to be absorbed, in the small intestine.
Regardless of the type of this operation, it should NEVER to be
undertaken lightly...it is dangerous surgery, and can be life-
threatening. However, if a person is morbidly obese (where the degree of
overweight, itself, is a threat to the person's survival), then sometimes
it is the only solution left...all other attempts at losing weight have
failed.
Whenever there is a problem with digestion (mechanically and
chemically breaking apart food in the gastrointestinal tract), there
usually is a following set of problems with absorbing nutrients from the
food-stuff into the body. For example, if the fat in the food eaten
hasn't been broken apart (mechanically) well enough in the stomach into
very small lipid/fat droplets, then the enzymes that come from the
pancreas and from the small intestine can't complete the digestion of the
fat. That means that too much fat-like substances get down further into
the large intestine...this creates greasy stools, which can be a
nuisance...but, also, there can be substantial kilocalories lost in the
fecal matter, but more importantly loss of some components of fat that are
essential to the functioning of the body (essential fatty acids).
To counteract some of the food-related problems that will happen
after a gastrectomy or stomach by-pass, recommendations include avoiding
large meals (because of the small stomach capacity), drinking liquids in
small amounts and not with meals, and being aware of the possible problem
of lactose intolerance (from the sugar in milk...lactose...not being
completely digested in the small intestine. Also, the patient must be
aware of the possiblity of long-term deficiencies of several B vitamins
and may need supplements of several vitamins.
I guess, if there is any good news to such a dismal set of
circumstances, it is that people really do lose a substantial amount of
weight after the by-pass, usually by about 2 years...but, some regain some
of the weight lost. Undoubtedly, the operation has saved some people's
lives or has vastly improved the quality of the formerly-obese person's
life.
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