|MadSci Network: Cell Biology|
Why, if macroscopic electroneutrality is not violated by cells, we do measure a voltage difference between cell's interior and extracellular milieu? Is it all due to infinitesimal differences all long the cytoplasmic membrane, acting as a capacitor (possessing a charging capacity inversely proportional its thickness)? Electrogenic pumps provide part of the answer, but the total cancelation of ion fluxes in steady-state seems quite arbitrary (but one need this assumption to derive equations such as Goldman-Hodgking-Katz).
Re: Do we really understand the resting membrane potential?
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