MadSci Network: Genetics
Query:

Re: how can a haploid organism be used in genetics problems( like sordaria)

Date: Wed Nov 26 10:42:46 2003
Posted By: Alex Brands, Post-doc/Fellow, Biological ciences, Lehigh University
Area of science: Genetics
ID: 1067357379.Ge
Message:

Hello Sanaz,

This is an interesting question, because genetic studies require the 
recombination 
of genetic information.  If an organism is haploid, each cell has only one copy 
of the 
genome, so how can there be any recombination of genes?

Although Sordaria spends most of its life cycle as a haploid, it can reproduce 
sexually.  This is accomplished by the fusing of two nuclei to form a diploid 
cell, and 
is followed by meiosis.  This yields four spores that can germinate to form 
four 
haploid individuals.  

Since Sordaria can go through sexual reproduction, one can study several 
genetic 
processes.  You could follow independent assortment of genes, look for 
epistasis, 
and generate genetic maps, which could include the physical order of genes 
along 
a chromosome as well as their relative distances. 

Haploid organisms offer some advantages in genetic studies, primarily in that 
you 
don't have to worry about "dominant" or "recessive" genes.  In a haploid, 
essentially 
all the genes are dominant, making them easy to study.  The downside to this is 
it is 
very difficult if not impossible to study lethal mutations in a haploid.

More detailed explanations along with diagrams can be found at the following 
web site.
 http://www.fgsc.net/sordnn16.html 

Alex





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