MadSci Network: Genetics |
Dear Joseph, Like all features of our anatomy, the size of the penis is ultimately judged by genes that were inherited from both our father, and mother. An example of such a genetic component can be found in cases of micropenis syndrome, in which slight changes in the sequence of a gene encoding the protein 5Alpha-Reductase Type 2 have been linked to abnormally small penis size, or even genital ambiguity. This protein is an enzyme which metabolises testosterone in the peripheral tissues, and would therefore be expected to play a more general role in growth and development. As such, it is unclear whether the role of the 5Alpha-Reductase Type 2 gene (or any other penis-size gene for that matter) is exclusively linked to the size of the penis. Moreover, specific dimensions, such as length or width are likely characterised by a complex interaction of genes rather that by one single gene. Although environmental factors may also play a significant role in the final size of a developing penis, these effects are hard to study because of their subtlety, ontop of the invasive nature of studying a developing fetus. However, the size of a flaccid, relaxed human penis is considerably sensitive to cold temperatures. A drop in temperature can lead to the diversion of blood flow from appendages in an effort to conserve body heat, resulting in decreased flaccid size of the highly vascularised penis. Hope that helps!
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