MadSci Network: Genetics |
First, if one is a carrier of a recessive allele, no phenotype (e.g. disease character) will be expressed from that gene (from that DNA strand) OR the transcript phenotype of the recessive allele will not have any effect on the organism. Second, if one is a carrier of a recessive allele without beeing predisposed to the recessive character, the allele is still part of is genomic DNA. So if the carrier has a baby with a non-carrier, the newborn has 1/2 chances of getting the recessive allele. If the carrier as a baby with a carrier for that same character, the baby has 1/4 chance of getting the recessive phenotype for that recessive character or 1/2 chance of beeing a carrier. Conclusion: a genetic counselor wouldn`t be able to do much more than to tell one 1) what are the chances of you having the recessive allele on one or both copies of that gene 2) saying one is carrier or ``affected`` with a reccessive allele, what chances that person and their lover has of getting a baby affected by that character and 3) what are the consequences of a baby with a recessive phenotype if there are any. All of this by analysing a genealogical tree of one's past relatives (or DNA testing, if it's available for that character). Of course this concept gets more complicated if the recessive allele is associated with the sex chromosomes, or the character is only present in one sex but not the other. The above probabilities apply only if the allele is present on one of the autosomes and has no sex-specific effect in males or females. Please ask again if you still have questions.
Try the links in the MadSci Library for more information on Genetics.