|MadSci Network: Biochemistry|
I was wondering if there are any proteins where the polypeptide chains intentionally link the N-terminus to the C-terminus to cyclize the chain? I thought some protein must do this since there's always a free amino and carboxy end floating around, but my TA didn't know of anything like this. Or could you have a protein with a lot of prolines that kinks around the ribosome as the peptide chain elongates so that it re-attaches with the C-terminal end?
Re: Are there any cyclized proteins?
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