if free radicals promote aging, then why is nitric oxide involved in the

MadSci Network: General Biology

Subject: if free radicals promote aging, then why is nitric oxide involved in the

Date: Mon Jan 9 13:56:02 2006
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Area of science: General Biology
ID: 1136840162.Gb

Message:


extension of life span in mammals? 

Upon reading an article published in Science titled: Caloric restriction 
promotes mitochondrial biogenesis by inducing the expression of eNOS, the 
article explains how caloric restriction (which is known to promote longevity), 
induces eNOS expression which is pretty much the precursor of the free radical 
gas nitric oxide. If free radical gases are a cause of aging, then why does NO 
promote longevity?

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