MadSci Network: Genetics |
Hi Sharon! Mc1r regulates melanogenesis in mammals - like mice, mamoths and humans - and thus is responsible for, e.g. their hair and skin color. So, it sure would be possible to "pick out" the gene for Mc1r in humans and/or other animals (even non-mammals, like reptiles etc have the Mc1r gene, even though it has somewhat of a different function there). And you wouldn't even have to take a hair to isolate this gene (infact hairs themself only contain very little DNA) - about any cell of the body would do, as almost every cell (apart from, for example, the red blood cells) contains the complete genome, i.e. all genes of the animal/human your looking at. I doubt however such a project can be easily performed at a high school since it involves some fancy machines (for example to carry out PCR or sequencing) and, depending on what you're trying to show, use of hazardous substances. Luckily, however, some other people have carried out such a project and you can at least have a look at the DNA and amino acid sequences of human Mc1r: Just go to:http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=27477128 and scroll all the way down. Erik
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