MadSci Network: Biochemistry |
I am in intro to Biochem and my professor gave me this problem for extra credit, and I really have no idea even where to begin on this. I've tried to find answers everywhere so I figured I try you: Your patient has a benign tumor of his Schwann cells, and and altered protein. An Experiment, in which you incubate the protein p21ras with this protein and measure what percentage of the guanine nucleotide bound to the p21ras is GTP, shows: Protein GTP/(GTP+GDP) on p21ras(%) Your patient's protein 50 Normal protein 5 a. What is the role of the protein that appears to be defective in you patient? How could the mutation cause the observed problem? b. Why might an inhibitor of farnesyltransferase help this disease?
Re: I dont know how to solve a problem like this???
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