MadSci Network: Cell Biology |
There have been debates as to whether or not male mitochondrial DNA (mtDNA) contributes during fertizilation. Some researches say less then 1% of mtDNA maybe donated from the father, a fairly insignificant amount all told. Other researches say that no mtDNA is transmitted via the father. But assuming it occured, there wouldn't be anything abnormal with the individual. Whether you have mtDNA from you mother or father or both wouldn't really matter much as mtDNA is it's own DNA structure, and as long as you have mtDNA from one parent, you'll have the ability to still produce ATP. The thing to remember about mtDNA is that, unlike chromosomes, mtDNA is not copied by the cell during cell replication, it is signaled by the cell that cell replication is occuring and the mitochondrion does it's own copying which is a very unique thing in itself. Also there isn't, technically speaking, a male mtDNA as every male inherits his from his mother. The sperm itself contains significantly fewer mitochondria then would be found in the egg so any donation that came from the sperm would be tiny.
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