Re: How would a sudden increase in Testosterone and drop in Estrogen effect me?

Ok, John - you thought in the right direction. An increase in 
testosterone through artificial means is definitely not natural, and can 
cause many problems. I'll explain in more detail, but first, let's take a 
quick peek at what exactly does testosterone do in our body.
Testosterone is a steroid hormone, formed in the testes, and a part of a 
group called androgens - meaning any steroid hormone, that has 
masculinizing effects. There is another hormone, found mostly in females, 
that is estrogen - causing feminizing effects. Both these hormones are 
secreted in the human body, albeit at different rates - males have more 
of testosterone and females have more of estrogen.
We'll concentrate on testosterone. This hormone has various effects in 
the body, starting from its effects in the mother's womb to its birh till 
the baby boy grows up and becomes an adult....and till a man lives.
Let's go stepwise. Testosterone in a male fetus (baby in the mother's 
womb)helps in formation of the male reproductive organs, suppressing the 
growth of female genital organs. Once the process is done with, 
testosterone secretion is decreased to below maintenance levels. The re-
secretion of testosterone occurs during puberty, when, it helps in the 
development of secondary sexual characteristics, like growth of hair over 
various parts of the body(apart from the head), further growth of the 
male genitalia, cracking of voice. In fact, increased testosterone is 
also responsible for the acne that adolescents have. The skin then slowly 
adapts itself to the increased level of testosterone, so by a few years 
time, acne resolves itself. Testosterone also helps in increasing muscle 
mass, a characteristic of the male body. 
Because of this effect of increasing muscle mass, testosterone has been 
widely used by athletes to enhance their performance. This practice is 
severely looked down upon, because of the long-term harmful effects of 
excessive testosterone. Also, it is wrong ethically, to do so.
So, what does excess testosterone actually do in the long run? Well, 
first of all,  its a steroid, and if you look up any book on medicines, 
you'll find that long term steroid use has a lot of harm. I can cause a 
rise in blood pressure, raised blood sugar, decreased amount of good 
cholesterol, more bad cholesterol, and hence an increased chance of heart 
related problems. In men, it also leads to a decrease in testicular 
function, including decreased formation of sperm and decreased secretion 
of a person's own natural testosterone - leading to infertility. 
So, overall, taking testosterone supplements is just like digging our own 
grave. Let's all say NO to steroids!!!
Hope this helps dispel your doubts....
Dr Ankur

Ref: Textbook of Medical Physiology, 9th edi, Guyon and Hall, Saunders 
publication