MadSci Network: Cell Biology

Re: Can an existing stem cell from a line be cloned?

Date: Thu Nov 15 12:43:52 2007
Posted By: William Gunn, Grad student, The Center for Gene Therapy, Tulane University
Area of science: Cell Biology
ID: 1193758881.Cb

Thanks for your question, J.

While it may be possible to do as you mention above, you would essentially be using a stem cell line to generate another stem cell line, a process that doesn't seem to have much purpose.

If you're interested in new developments in somatic cell nuclear transfer(the more correct name for the process, as it's not really cloning in the sense we normally use the word), you could do no better than to follow the work of Rudolph Jaenisch. His most recent work involved reprogramming a somatic cell to an ESC-like state without nuclear transfer, simply by turning on some genes already present in the cell.

Apologies for the delay in the answer, I only got the reminder email, not the original one.

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