MadSci Network: Anatomy

Re: how can you control the glycogen metabolism in the liver?

Date: Tue Jan 8 14:09:27 2008
Posted By: Gabriel Keith Harris, Assistant Professor, Department of Food Science
Area of science: Anatomy
ID: 1198851706.An

These are very interesting questions.

My understanding is that hunger is only partially influenced by blood sugar per se and that hormones such as leptin and ghrelin also play a role in the hunger response.

Other than breaking muscle tissue down, converting it to the sugar glucose (via deamination and gluconeogenesis) and using that sugar to maintain glycogen levels, I am not sure that there is a way to maintain glycogen levels.

Even if this were possible (I'm not sure that it is) using a supplement or a drug, loss of muscle tissue would not be considered a positive outcome.

Since I believe that you are really asking how to stave off hunger and prevent weight gain, I would say that the best strategies would be:

1) to eat regularly (at least 3 times per day);
2) to consume a serving of protein at each meal (protein seems to be the most satiating of the macronutrients);
3) to consume a variety of low-glycemic index starches, fruits, and vegetables in order to help maintain blood sugar levels; and
4) to exercise regularly (using a combination of resistance and aerobic exercise) in order to increase metabolic rate.

glycemic index

protein and satiety


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