Subject: How can a contour length of an isolated covalently closed circular (ccc) DNA molecule be measured?
Date: Mon Jun 8 06:59:37 2009
Posted by Nina
Grade level: undergrad
School: Faculty of Science, Charles University
City: Prague State/Province: No state entered.
Country: Czech Republic
Area of science: Molecular Biology
Are there any standards for comparison? Because it is a covalently closed circular (ccc) molecule,
I can't measure the contour length as it is in the microscope. I've read more, and I think there is
some connection to open circular (oc) DNA form. Does that mean I should nick the ccc DNA
molecule to oc DNA molecule and then measure the length? Thank you
Re: How can a contour length of an isolated covalently closed circular (ccc) DNA molecule be measured?
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