|MadSci Network: Biochemistry|
In a response to "How does Histamine aid in the secretion of gastric acid", your reply included the following: "Like many activities our body must carry out, stomach acid production is highly regulated. Many stomach diseases (such as ulcers and GERD) are either directly or indirectly caused by a lack of regulation of HCl in the stomach. In this way, stomach acidity can be decreased by blocking vagus nerve stimulation, by blocking gastrin- releasing peptide release, by blocking gastrin release, or by blocking histamine release." It seems that the popular perception has been that GERD, gastritis, etc is caused by the presence of too much HCl, but I have also read that it is actually caused by too little and that the way to correct this is by supplementing with add'l HCl, rather than suppress acid or histamine. Which is it?
Re: Are gastric complaints caused by too much HCl or too little HCl?
Try the links in the MadSci Library for more information on Biochemistry.