|MadSci Network: Biochemistry|
The compound "Splenda", uses a sugar that is the opposite stereoisomer to the glucose we can absorb and metabolize. This material is not able to be metabolized. My questions are: a. It may not be metabolized, but it may be absorbed (at least to some degree) by physical processes such as diffusion due to its concentration gradient between intestine and bloodstream. Does this happen? And to what degree? b. Given some level of absorbtion, the material will then "wander around" in the blood...it can't be metabolized. No doubt this level can't get too high (or it'll diffuse back out into the gut again), but if there is any, does it have any subsequent effects? Specifically, can the kidneys excrete it? Will it show up as "sugar" on blood tests for diabetes (these tests are not metabolic, so the chemistry may detect both stereoisomers)?
Re: Physiological and medical effects of l-stereoisomeric sugar
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