MadSci Network: Genetics
Query:

Re: Can you replace older woman's zona pellucida with younger donor zp for IVF

Date: Fri Oct 15 11:48:03 2010
Posted By: R. James Swanson, Professor, Biological Sciences & Obstetrics and Gynecology; Graduate Program Director, PhD in Biomedical Sciences Program
Area of science: Genetics
ID: 1286583777.Ge
Message:

LB, The technique of ZP replacement is quite tricky and requires a 
technician with very good micromanipulation skills.  Once done, if the 
embryo’s blastomeres have not been damaged, no untoward genetic 
consequences would accrue to the child that were not part of his or her 
genetic makeup to begin with.  No genetic information resides in the ZP 
so it doesn’t matter who’s ZP is used as long as it is reproductively 
competent and the transfer technique is performed successfully.


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