| MadSci Network: Anatomy |
There are many phsiological effects of the sun, and it gets a little muddled and complicated because several hormones are involved. The involved hormones have multiple effects on the body. The Vitamin D effect, which you mentioned, is one of the best studied effects of sun exposure. Sunlight can also cause the release of POMC (pro-opiomelanocortin). This is a peptide hormone that is split up into about 5 active short peptide hormones which have a variety of effects on the body. The proopiomelanocortin (POMC) gene encodes the common precursor for MSH-related and beta-endorphin-related end products. One of the hormones, MSH, melanocyte stimulating hormone, causes some skin cells to start making melanin. Melanin makes you brown. This stimulation is why you tan when you go into the sun. If you would like to learn more about POMC, and its varied and interesting effects on the body, see: http://www.ultranet.com/~jkimball/BiologyPages/M/MSH.html Another well studied effect is that of UV radiation on skin cells. As you probably know, exposure to UV rays from the sun can damage DNA by causing thymine (the T in ACGT) to dimerize. When two of these thymine dimers are excised from DNA by the DNA damage surveillance machinery, a double strand break can be caused, leading to loss of part of a chromosome. Enough of this sort of damage can lead to cancer. Here is some more information about skin cancer: http://www.maui.net/~southsky/introto.html Erin
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