MadSci Network: Medicine
Query:

Re: Can the AIDS virus be killed by Microwaves of same wavelength as dia of it?

Area: Medicine
Posted By: Brian Foley, Post-doc/Fellow Molecular Genetics
Date: Mon Jul 14 14:19:14 1997
Area of science: Medicine
ID: 865789288.Me
Message:
	The Human Immunodeficiency Virus can be inactivated by 
many things, including exposure to air.  It cannot be passed from
one person to another by coughing or sneezing because it is
a very fragile RNA virus that cannot survive exposure to air or
drying conditions.  So we cannot test it's survival in a 
microwave, because it is already killed by the air in the
microwave.
	If you want to "kill" HIV in a person, you have to destroy
more than viral particles.  HIV is a retrovirus, which means it
copies its RNA genome into DNA, and that viral DNA is then inserted
into the host chromosomes before new virus can be made.  Thus
if you "kill" virus particles, more particles can still be
made from the viral template that is in the host chomosomes.
It would be analagous to destroying the bombs of a country but not
destroying the bomb factories, so the country just builds more
bombs.
	Another part of your question that does not make
sense, is the question of wavelength.  The HIV viral particle
is about 60 nanometers (0.06 micrometers) in diameter.  I don't
think a wave of that length would be a microwave, but I could
be wrong (I'm a genetecist, not a physicist).  The virus is
made up of proteins and nucleic acids, and agents which would
destroy these compounds would also destroy the host cells.  
It is easy to destroy the virus outside the host, it is very
dificult to destroy it inside the host, without also damaging
the host.



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