Date: Fri Dec 29 03:19:57 2000
Posted By: Elsa Lee, Grad student, Molecular Cell Biology, University of California, Berkeley
Area of science: Anatomy
ID: 971038205.An
Message:
Dear Jay,
Here is a fairly detalied answer to your question I found at the website
for www.britannica.com.
Eye blinking:
In the waking hours the eyes blink fairly regularly at intervals of two to
10 seconds, the actual rate being a characteristic of the individual. The
function of this is to spread the lacrimal secretions over the cornea. It
might be thought that each blink would be reflexly determined by a corneal
stimulus--drying and irritation--but extensive studies indicate that this
view is wrong; the normal blinking rate is apparently determined by the
activity of a "blinking centre" in the globus pallidus of the caudate
nucleus, a mass of nerve cells between the base and the outer substance of
the brain. This is not to deny that the blink rate is modified by external
stimuli.
There is a strong association between blinking and the action of the
extraocular muscles. Eye movement is generally accompanied by a blink, and
it is thought that this aids the eyes in changing their fixation point.
Secretion of tears
The exposed surface of the globe (eyeball) is kept moist by the tears
secreted by the lacrimal apparatus, together with the mucous and oily
secretions of the other secretory organs and cells of the lids and
conjunctiva; these have been described earlier. The secretion produces
what has been called the precorneal film, which consists of an inner layer
of mucus, a middle layer of lacrimal secretion, and an outer oily film
that reduces the rate of evaporation of the underlying watery layer. The
normal daily (24-hour) rate of secretion has been estimated at about 0.75
to 1.1 grams (0.03-0.04 ounce avoirdupois); secretion tends to decrease
with age. Chemical analysis of the tears reveals a typical body fluid with
a salt concentration similar to that of blood plasma. An interesting
component is lysozyme, an enzyme that has bactericidal action by virtue of
its power of dissolving away the outer coats of many bacteria.
Tears are secreted reflexly in response to a variety of stimuli--e.g.,
irritative stimuli to the cornea, conjunctiva, nasal mucosa; hot or
peppery stimuli applied to the mouth and tongue; or bright lights. In
addition, tear flow occurs in association with vomiting, coughing, and
yawning. The secretion associated with emotional upset is called psychical
weeping. Severing of the sensory root of the trigeminal (fifth cranial)
nerve prevents all reflex weeping, leaving psychical weeping unaffected;
similarly, the application of cocaine to the surface of the eye, which
paralyzes the sensory nerve endings, inhibits reflex weeping, even when
the eye is exposed to potent tear gases. The afferent (sensory) pathway in
the reflex is thus by way of the fifth cranial, or the trigeminal nerve.
The motor innervation is by way of the autonomic (involuntary) division;
the parasympathetic supply derived from the facial nerve (the seventh
cranial nerve) seems to have the dominant motor influence. Thus, drugs
that mimic the parasympathetic, such as acetylcholine, provoke secretion,
and secretion may be blocked by such typical anticholinergic drugs as
atropine. Innervation of the lacrimal gland is not always complete at
birth, so that the newborn infant is generally said to cry without
weeping. Because absence of reflex tearing fails to produce any serious
drying of the cornea, and surgical destruction of the main lacrimal gland
is often without serious consequences, it seems likely that the subsidiary
secretion from the accessory lacrimal glands is adequate to keep the
cornea moist. The reflex secretion that produces abundant tears may be
regarded as an emergency response.
A drainage mechanism for tears is necessary only during copious secretion.
The mechanism, described as the lacrimal pump, consists of alternately
negative and positive pressure in the lacrimal sac caused by the
contraction of the orbicularis muscle during blinking.
I hope this satisfies your curiosity =)
Have fun with science!
Elsa
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